Antibiotic	Gram-positive cocci						Gram-negative bacilli							Gram-negative cocci		Anaerobes			Atypicals
	MRSA	MSSA	Strep	Pneumo	E. faecalis	VRE	E. coli	P. mirabilis	Klebsiella	Pseudomonas	ESCAPPM	H. flu	Acinetobacter	N. gonorrhoeae	N. meningitidis	Oral anaerobes	B. fragilis	C. diff	Mycoplasma	Legionella	Chlamydia
Penicillin GIVPenicillins			94		99
Nafcillin / OxacillinIVPenicillins	0	100
Ampicillin / AmoxicillinIV / POPenicillins					100	31	57	92	IR	IR	IR
Cefazolin / CephalexinIV / POCephalosporins · 1st							74	IR	79	IR	IR
Cefoxitin / CefotetanIVCephalosporins · 2nd (cephamycin)
CeftriaxoneIVCephalosporins · 3rd			100				88	98	86	IR	69
CeftazidimeIVCephalosporins · 3rd							88	96	86	96	72
CefepimeIVCephalosporins · 4th							89	99	86	95	88
Amoxicillin-clavulanatePOβ-lactam / β-lactamase inhibitor							79	96	85	IR	IR
Ampicillin-sulbactamIVβ-lactam / β-lactamase inhibitor							60	94	75	IR	IR
Piperacillin-tazobactamIVβ-lactam / β-lactamase inhibitor							88	99	83	92	72
ErtapenemIVCarbapenems							100	100	100	IR	95
Meropenem / ImipenemIVCarbapenems							100		100	93	100
AztreonamIVMonobactam							89	99	86	91	74
CiprofloxacinIV / POFluoroquinolones	17	95					76	83	81	86	88
LevofloxacinIV / POFluoroquinolones					86	33
MoxifloxacinIV / POFluoroquinolones	30	95
Gentamicin / Tobramycin / AmikacinIVAminoglycosides							91	96	95	98	98
ClindamycinIV / POLincosamides	77	83	77
AzithromycinIV / POMacrolides
DoxycyclineIV / POTetracyclines	88	97			44	75	77	IR	79	IR	93
VancomycinIV / POGlycopeptides	100	100	100		97	72
TMP-SMX (Bactrim)IV / POFolate antagonists	89	99					81	93	83	IR	87
MetronidazoleIV / PONitroimidazoles
LinezolidIV / POOxazolidinones	100	100			98	89
DaptomycinIVLipopeptides	100	100			81	100